Skin Regeneration - Oxiproteomics

Proven benefits of skin Renewal Claims

The skin naturally regenerates every 28 days through a cycle of cell division, cell differentiation and migration from the deepest layer of the epidermis to the surface.

This process slows with age, or may be compromised by daily stress and environmental factors. However, by using performant skincare products targeting cell function and maintenance, we can preserve the skin’s regenerative abilities, which is crucial for maintaining a youthful and healthy appearance.

Proven benefits of promoting skin renewal and regeneration include improved texture, reduced signs of aging, and a stronger barrier against UV radiation, microorganisms, and dehydration. Effective skincare is essential for keeping the skin vibrant and functional as we age and face daily stressors.

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models available

2d/ 3d/ co-culture/ in-vivo

Stressor Used

without STRESsors (basal)/ UV irradiation/ blue light (hev)/ indoor & outdoor pollution/ chemical or biological stressors (e.g inflammatory cytokines)

Typical Concerns

skin regeneration/ skin barrier

EXPLORE OUR INNOVATIVE TESTING

In the example, in an ex vivo model of compromised skin (mechanical disruption) we have evaluated the ability of a topical product to restore and strength the natural skin barrier function.

These images highlight the powerful effect of a skincare product on activating the regenerative process of the skin to restore the barrier function

Compromised skin (Before):
The left image shows a thin skin barrier leaving it more vulnerable to daily environmental stressors like UV exposure and pollution.

Renewed skin (After):
The product remarkably restored the skin barrier in only 5 days by increasing the thickness and number of layers of the epidermis and stratum corneum

BEFORE

AFTER

Showing the product’s regenerative effect on the skin barrier by increasing the cornified layers in the stratum corneum, the outermost part of the skin.

SCIENTIFICALLY PROVEN RESULTS

At OxiProteomics, we empower you to substantiate your “skin regeneration” claims with robust scientific validation, building consumer trust and demonstrating the real, measurable benefits of your product.

Our cutting-edge biological models and advanced targeted evaluations are designed to assess how your products enhance skin renewal, protect against aging and environmental stressors, and promote recovery from damage.

With precise, science-backed evidence, we showcase the efficacy of your active ingredients or formulations, highlighting their impact on the intricate processes and interactions essential for effective skin regeneration. This ensures your claims are both credible and compelling, setting your brand apart in the competitive skincare market.

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Visibly renewed Skin Barrier After Application of Product.

WHO WE ARE

OxiProteomics is a CRO specialized in biomarker assessment providing research services for skin- & hair-care dermo-cosmetics, food supplements, medical devices, and dermatology efficacy evaluation.

Spined-out from Sorbonne University in 2014, our uniqueness is a specific know-how on non-targeted & targeted proteomics approaches adapted to skin and hair evaluation. We support our clients on molecular target identification, target validation, efficacy testing, mechanistic studies, prediction of responders, and biomarkers discovery.

We also propose predictive pre-clinical skin models coupled with spatial proteomics analyses, based on the organ culture of human skin samples. We also able work with clinical samples to perform bio-analysis. We also provide mechanistic investigator-initiator trials with the analysis of biopsies and non-invasive samples.

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