PROVEN BENEFITS OF SKIN DETOXIFICATION CLAIMS

Today’s consumers are more knowledgeable than ever about how daily environmental aggressors contribute to cumulative skin damage and dysfunction. This growing awareness fuels demand for skincare products that actively support the skin’s natural detoxification and recovery processes.

At OxiProteomics, we provide scientific validation of your product’s ability to boost the skin’s natural detox mechanisms. Our advanced testing targets key biomarkers, such as oxidatively damaged (carbonylated) proteins, which accumulate due to daily stress and aging.

By demonstrating your product’s effectiveness in eliminating these toxic compounds, you can strengthen your detox claims and appeal to consumers seeking clearer, healthier, and more radiant skin.

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ModeLs available

2d/ 3d in vitro & ex vivo skin models/ 2D Co-culture/ In-vivo (E.g. Tape stripping)

Stressor Used

Basal(No stress induction)/ uv irradiation/ Indoor & outdoor pollution/ blue light (HEV)/ chemical or biological aggressions (including neuro-inflammatory stimuli)

Typical Concerns

revitalised skin/ skin vitality/ Uneven Skin tone/ inflammation/ Dullness/ skin detoxification

EXPLORE OUR INNOVATIVE TESTING

A crucial indicator of oxidative stress and aging in skin is protein carbonylation, a marker for oxidatively damaged proteins. Monitoring and reducing levels of carbonylated proteins is key to detoxifying and rejuvenating skin. By analyzing these proteins, we provide essential insights into enhancing the skin’s ability to combat environmental stressors.

The accompanying images illustrate the effect of a detoxifying compound on carbonylated proteins.

Before treatment, the left image shows high levels of these proteins (in red), affecting the stratum corneum, epidermis, and dermis.

After treatment, the right image displays a significant reduction in these compounds, indicated by a reduced red colour, demonstrating the product’s effectiveness in reducing oxidative damage and restoring skin vitality by stimulating the detoxification of carbonylated proteins, maintaining skin long-term health and functionality.

BEFORE

AFTER

Showing the benefit of product on carbonylation levels (in red).

Before: High levels of carbonylated proteins indicate significant oxidative damage in the skin (on stratum corneum, epidermis, and dermis). After: Post-treatment shows a marked reduction in skin carbonylation levels, highlighting the product’s effectiveness in enhancing skin detoxification.

Scientifically proven results

Assessing biomarkers of oxidative damage, such as carbonylated proteins, provides solid scientific evidence to support your product’s ability to detoxify the skin and reverse the cumulative damage caused by daily environmental stressors. With OxiProteomics, you gain scientifically validated proof that your product delivers real detoxification benefits—building trust and setting your brand apart in the skincare market.

Target Audience: Attract consumers looking for advanced solutions that not only rejuvenate but also detoxify skin, contrasting the effects of aging and environmental exposure.

Premium Positioning: Position your product as a high-performance skincare innovation that not only supports the skin’s natural detoxification processes but also addresses the fundamental concerns of aging and oxidative stress.

Partner with OxiProteomics to gain precise insights into your product’s detoxification performance and create impactful, scientifically grounded marketing strategies that connect with your target audience and enhance your brand’s reputation.

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Visibily reduced oxidative damage after application of product.

WHO WE ARE

OxiProteomics is a CRO specialized in biomarker assessment providing research services for skin- & hair-care dermo-cosmetics, food supplements, medical devices, and dermatology efficacy evaluation.

Spined-out from Sorbonne University in 2014, our uniqueness is a specific know-how on non-targeted & targeted proteomics approaches adapted to skin and hair evaluation. We support our clients on molecular target identification, target validation, efficacy testing, mechanistic studies, prediction of responders, and biomarkers discovery.

We also propose predictive pre-clinical skin models coupled with spatial proteomics analyses, based on the organ culture of human skin samples. We also able work with clinical samples to perform bio-analysis. We also provide mechanistic investigator-initiator trials with the analysis of biopsies and non-invasive samples.

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