Our scientific team provides solutions for efficacy validation from biological screening of new actives up to marketing claims of finished products:
Carbonyl screen is a method allowing to test in situ the protective effect of several actives at different concentrations upon different type of stress (Blue light, UV-A, Pollution, oxidative stress) using in vitro models of skin cells.
This first approach adapted to high-throughput screening allows defining the most promising actives and their optimal concentration for further studies.
In situ vizualisation of molecular damage protection
Imaging approaches allows the visualization of the proteins protected from the oxidation by your product, on cells or skin layers (derm, epidermis, stratum corneum).
The tested products can be applied on biological models (cells or skin explants) subjected to different type of stress (Pollution, UV-A, Blue light).
Quantification of molecular damage protection
This service provides a reliable read-out parameter for the efficacy testing of actives and finished products. We will evaluate the capacity of your product to protect human skin from stress (Pollution, UV-A, Blue light) induced molecular damage (protein oxidation) by a total quantification of oxidized proteins with high sensitivity and reproducibility. You will benefit of quantitative analysis under the form of Efficacy score.
Your actives can be tested on the biological model of your choice (cells or skin explants).