CELLULAR SENESCENCE: A BARRIER TO HEALTHY AGING

Cellular senescences of skin cells significantly contribute to visible signs of skin aging, including wrinkles, sagging, and age spots.

As cells become senescent, they lose their ability to function properly and begin releasing inflammatory factors (SASP) that accelerate skin deterioration.

At OxiProteomics, we offer advanced testing solutions to support cosmetic and skincare brands in developing and validating effective anti-aging products. Our cutting-edge assays measure specific senescence markers, providing scientific proof of your product’s ability to combat skin aging at its source.

Explore our innovative testing

We provide advanced testing solutions specifically designed to evaluate the efficacy of senomorphic (senescence-modulating), senostatic (senescence-delaying) and senolytic (senescent cell-clearing), skincare products.

One key marker of cellular senescence is P16, a protein that increases as cells age. By understanding and modulating P16 expression, we can unlock the secrets to maintaining youthful, radiant skin.

The provided images show a comparison between a senescent aged(before) skin explant and upon  treatment with a specific senolytic compound (after) . The red signal  indicates the presence of p16.

Key Observations:

Reduced Senescence: The “after” image shows a significant decrease in red staining compared to the “before” image. This reduction in p16 expression indicates a decrease in the number of senescent cells within the treated skin explant.

Improved Skin Health: Fewer senescent cells can lead to healthier skin. Senescent cells are known to release inflammatory factors that contribute to skin aging, such as wrinkles, age spots, and loss of elasticity. By reducing senescence, the treatment may help improve the overall appearance and texture of the skin.

SCIENTIFICALLY PROVEN RESULTS

The assessment of senescence biomarkers provides robust scientific proof to support your product’s anti-aging claims, strengthening marketing messages and setting your product apart from competitors.

Target Audience: Appeal to consumers seeking effective solutions to combat skin aging and maintain a youthful, radiant complexion.

Premium Positioning: Position your product as a high-performance anti-aging solution that directly targets cellular senescence, the root cause of skin aging.

Partner with OxiProteomics to unlock powerful insights into your product’s efficacy and build impactful, science-backed marketing strategies to engage your audience.