PROVEN ANTIOXIDANT EFFICACY

Antioxidants are essential in skincare, shielding skin from daily environmental stressors like UV rays and urban pollution, and combating oxidative stress—a key factor in skin aging.

At OxiProteomics, we provide robust scientific validation of the benefits of your antioxidant products (active compounds and formulations). Discover how our specialized assays,underscoring the activation of the skin’s natural antioxidant defenses, showcase your product’s ability to strengthen the skin’s resilience against oxidative stress—effectively minimizing damage and promoting a visibly healthier, more radiant, and youthful complexion.

Our advanced testing platform combines in-vitro and ex-vivo human skin models (100% animal free) with precise biomarker detection to deliver clear, measurable evidence of product efficacy. This comprehensive approach enhances your product’s credibility and strengthens your marketing claims. We also offer in vivo biomarker assessment through non-invasive tape stripping techniques, enabling real-world evaluation of product  performance directly on human skin upon product application.

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EXPLORE OUR INNOVATIVE TESTING

These images highlight the powerful effect of an antioxidant skincare product on activating the Nrf2 pathway, a key protein that protects the skin from environmental damage and accelerated aging.

Before (Faint Red):
The left image shows low Nrf2 levels in aged skin, leaving it more vulnerable to daily environmental stressors like UV exposure and pollution.

After (Bright Red):
The right image reveals a significant increase in the skin’s antioxidant defenses, a boost of over 80% was observed.

This enhanced Nrf2 activation (in red) demonstrates that the product effectively stimulates the skin’s natural protective mechanisms, boosting its resilience against oxidative stress and promoting a healthier, more youthful appearance.

BEFORE
AFTER

NRF2 stimulation (shown in red) upon the application of a product that enhances natural antioxidant defense mechanisms against oxidative stress..

Scientifically proven results

Our advanced testing clearly shows that the product has effectively “switched on” the skin’s natural protective mechanisms, enhancing its resilience and ability to combat daily environmental stressors.

This compelling visual evidence sets your product apart, providing scientifically validated proof of its efficacy in strengthening the skin’s defenses and promoting a healthier, more youthful-looking complexion.

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Induction of the skin’s natural antioxidant defenses through stimulation of the NRF2 pathway following product treatment.

WHO WE ARE

OxiProteomics is a CRO specialized in biomarker assessment providing research services for skin- & hair-care dermo-cosmetics, food supplements, medical devices, and dermatology efficacy evaluation.

Spined-out from Sorbonne University in 2014, our uniqueness is a specific know-how on non-targeted & targeted proteomics approaches adapted to skin and hair evaluation. We support our clients on molecular target identification, target validation, efficacy testing, mechanistic studies, prediction of responders, and biomarkers discovery.

We also propose predictive pre-clinical skin models coupled with spatial proteomics analyses, based on the organ culture of human skin samples. We also able work with clinical samples to perform bio-analysis. We also provide mechanistic investigator-initiator trials with the analysis of biopsies and non-invasive samples.

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With our deep understanding of proteomics and the cosmetic industry, we can help you unlock the full potential of your research and bring innovative, high-performing products to market.